1,2,4-triazine derivatives for the treatment of viral infections

摘要

This invention relates to 1,2,4-triazine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.;

主权项

1. A compound of formula (I)or a pharmaceutically acceptable salt, tautomer(s), or solvate thereof, wherein:
R1 is C1-6alkyl, arylalkyl, or heteroarylalkyl each of which is optionally substituted by one or more substituents independently selected from halogen, hydroxyl, amino, C1-6 alkyl, di-(C1-6)alkylamino, C1-6 alkylamino, C1-6 alkoxy, C3-6 cycloalkyl, carboxylic acid, carboxylic ester, carboxylic amide, heterocycle, aryl, alkenyl, alkynyl, arylalkyl, heteroaryl, heteroarylalkyl, and nitrile, and R2 is C1-8 alkyl, optionally substituted by one or more substituents independently selected from halogen, hydroxyl, amino, C1-3 alkyl, C1-3 alkoxy, C3-6 cycloalkyl, carboxylic acid, carboxylic ester, carboxylic amide, di-(C1-6)alkylamino, C1-6 alkylamino, aryl, heteroaryl, heteroarylalkyl and nitrile.