发明名称 SALI MISTI DI AMMINOACIDI ESSENZIALI O SEMI-ESSENZIALI E LORO ANALOGHI NON AZOTATI, NONCHE' LORO IMPIEGO NELLA TERAPIA DI DISFUNZIONI RENALI ED EPATICHE.
摘要 Novel compounds are prepared by reacting essential or semi-essential amino acids with nitrogen-free analogues thereof, particularly alpha-keto and/or alpha-hydroxy analogues. The mixed salt reaction products are precursors of essential and semi-essential amino acids in the body, and mixtures of the salts are useful in the treatment of renal and hepatic disorders characterized by protein intolerance leading to deficiencies of various essential and semi-essential amino acids in the body. They may also be useful in the treatment of nitrogen wasting disorders and protein malnutrition. The novel compounds are generally far more palatable and soluble in aqueous solutions than the individual essential or semi-essential amino acids, nitrogen-free analogues thereof, or simple mixtures of these.
申请公布号 IT8021498(D0) 申请公布日期 1980.04.18
申请号 IT19800021498 申请日期 1980.04.18
申请人 THE JOHNS HOPKINS UNIVERSITY 发明人 WALSER MACKENZIE
分类号 A61K31/19;A61K31/195;A61K31/40;A61P1/16;A61P3/00;A61P13/02;A61P15/00;C07C67/00;C07C229/22;C07C229/26;C07C241/00;C07C251/02;C07D209/20;C07D233/54;C07D233/64;(IPC1-7):A61K/ 主分类号 A61K31/19
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