METHOD OF PRODUCING ANTIBODY ERYTHROCYTIC PASTEURELLOSIS DIAGNOSTICUM

摘要

FIELD: veterinary science. ^ SUBSTANCE: invention refers to veterinary microbiology and biotechnology, can be used for development of specific diagnostic aids. According to the invention the method covers producing antibody erythrocytic pasteurellosis diagnosticum by carrier processing with serum antibodies of Pasteurella antigens being capsular antigens extracted from Pasteurella cultures with 2.0-2.5% sodium chloride brine at 40-42C during 30-40 min, with centrifuging the extract, separating the supernatant thereafter warmed up at 65-70C during 15-30 min followed with sterilisation filtration. The serum antibodies for making diagnosticum are gamma globulin fraction or G or M immunoglobulins. ^ EFFECT: application of the method allows for high-quality end product due to improved sensitivity and specificity. ^ 2 cl, 9 ex