| 摘要 |
<p>Genomic DNA and cDNA encoding the human NK-2 receptor is cloned and the recombinant protein expressed. Recombinant receptor and receptor fragments are used as therapeutics to treat disease, such as asthma. The recombinant receptor and receptor fragments are also used in methods of screening candidate compounds for their ability to antagonize interaction between the neurokinin A neurotransmitter and NK-2 receptor. Antibodies specific for NK-2 receptor and their use as a therapeutic and/or a vaccine is also disclosed.</p> |
