METHOD FOR PREPARATION OF HERBAL COMPOSITION INCREASED FAT-SOLUBLE POLYPHENOLS, HERBAL COMPOSITION PREPARED THEREBY, AND USING THEREOF

摘要

The present invention relates to a method for preparing a herbal composition having an increased fat-soluble polyphenols content, a herbal composition prepared thereby, and uses thereof. The herbal composition having an increased fat-soluble polyphenols content, was confirmed to have a significantly increased content of a fat-soluble polyphenol including decursin compared to herbal compositions of comparative examples. More notably, the herbal composition showed antioxidant action, immune cell activation effect and inhibition effect on cancer cell growth, and a significant decrease to normal levels of nephrotoxicity and hepatotoxicity induced by the anticancer drug, cisplatin, and further showed a significantly higher alleviating effect on radiation-induced loss of intestinal crypt, compared to the herbal compositions of comparative examples. Therefore, the herbal composition having increased fat-soluble polyphenols content can be beneficially used as a composition for treating cancer, an anti-cancer supplement, a composition for enhancing immune function, a protective composition and a composition for preventing the side effects of cancer treatment.