| 摘要 |
PURPOSE:To obtain the titled compound useful as an intermediate for producing arbutin, etc., in high yield, by reacting beta-pentaacetylglucose with hydroquinone using a (poly)ethylene glycol dialkyl ether as a reaction solvent and acetylating the resultant product. CONSTITUTION:beta-Pentaacetylglucose is reacted with hydroquinone using a mono- and/or polyethylene glycol dialkyl ether (preferably having >=140 deg.C boiling point, e.g. ethylene glycol dibutyl ether, etc.) as a reaction solvent to form tetraacetylarbutin, which is directly without isolation acetylated with an acetylating agent to afford the aimed compound expressed by the formula. The acetylating agent is preferably used in an amount or more required to completely acetylate the tetraacetylarbutin and residual hydroquinone.
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