摘要 |
FIELD: production of esters of aminobenzoic acids, some of them being biologically active compounds may be used in medicine. SUBSTANCE: process of liquid phase hydrogenation of esters of nitrobenzoic acids is carried out in the presence of supported palladium-containing catalysts. Nickel catalyst which is modified by palladium and which also comprises ferrum, or palladium catalyst catalyst comprising ferrum are used as mentioned above supported catalysts. Said nickel catalyst comprises 0.07-0.25 % of nickel, 0.05-0.3 % of ferrum (as calculated for mass of carrier), ratio of nickel and palladium in it being 1:1-0.5. Mentioned palladium catalyst comprises 0.07-0.6 % of palladium and 0.05-0.55 % of ferrum (as calculated for mass of carrier). Palladium is supported on carrier with by adsorption, aqueous solution its chlorohydroxocomplexes being used; mass ratio of hydroxide of alkali metal and palladium being 0.25-0.65:1. EFFECT: decreased specific expense of precious metals, improved purity of desired product, increased efficiency of hydrogenation of esters of nitrobenzoic acids. 5 cl, 1 tbl |