发明名称 Beta-lactam contng carboxylic acids salts-by cation - exchange pharmaceuticals
摘要 The salts esp. penicillin and cephalosporin derivs, are prepd in high yield and purity under mild conditions by cation exchange. A trialkyl or triaryl silyl ester of the acid is reacted with R'OM, (where M is the cation required in the prodcut, and R' si acyl, alkyl, aryl, Si(alkyl)3 ro Si(aryl)3) in an aprotic solvent contg. insufficient H2O or alcohol for complete hydrolysis of the ester.
申请公布号 DE2026506(A1) 申请公布日期 1971.12.16
申请号 DE19702026506 申请日期 1970.05.30
申请人 发明人
分类号 C07D499/00;C07D499/16;(IPC1-7):07D99/14 主分类号 C07D499/00
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