| 发明名称 |
CAMPTOTHECIN DERIVATIVES HAVING ANTITUMOR ACTIVITY |
| 摘要 |
Derivatives of camptothecin of formula (I) <CHEM> wherein the groups R1, R2 and R3 are as defined in the description are disclosed. The compounds of formula (I) are endowed with antitumor activity and show a good therapeutic index. Processes for the preparation of the compounds of formula (I) and their use in the preparation of medicaments useful in the treatment of tumors are also disclosed. |
| 申请公布号 |
PL222208(B1) |
申请公布日期 |
2016.07.29 |
| 申请号 |
PL20000355094 |
申请日期 |
2000.03.08 |
| 申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.;ISTITUTO NAZIONALE PER LO STUDIO E LA CURA DEI TUMORI |
发明人 |
PENCO SERGIO;MERLINI LUCIO;ZUNINO FRANCO;CARMINATI PAOLO |
| 分类号 |
C07D491/22;A61K31/435;A61K31/4745;A61P31/12;A61P33/06;A61P35/00 |
主分类号 |
C07D491/22 |
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