Antigen specific plasmacytomas and antibodies derived therefrom.
摘要
<p>Disclosed herein is a method for producing antibodies against an antigen of interest. Animal cells are exposed to both the antigen of interest and a recombinant retroviral vector. The vector contains a combination of oncogenes capable of inducing plasmacytomas. Plasmacytoma formation takes place rapidly and takes place in the presence of the antigen. A very high proportion of the plasmacytomas that are recovered are antigen specific.</p>
申请公布号
EP0455512(A1)
申请公布日期
1991.11.06
申请号
EP19910304051
申请日期
1991.05.03
申请人
WISCONSIN ALUMNI RESEARCH FOUNDATION;UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES
发明人
RISSER,REX G.;LARGAESPADA,DAVID A.;MUSHINSKI,JOSEPH F.;WEISSINGER, EVA M.;MISHAK, HARALD