发明名称 |
Combination therapy for treating hypercholesterolemia |
摘要 |
The invention relates to methods for treating hypercholesterolemia and atherosclerosis, and reducing serum cholesterol in a mammal. The methods of the invention comprise administering to a mammal a first amount of a bile acid sequestrant compound which is an unsubstituted polydiallylamine polymer and a second amount of a cholesterol-lowering agent. The first and second amounts together comprise a therapeutically effective amount. The invention further relates to pharmaceutical compositions useful for the treatment of hypercholesterolemia and atherosclerosis, and for reducing serum cholesterol. The pharmaceutical compositions comprise a combination of a first amount of an unsubstituted polydiallylamine polymer compound and a second amount of a cholesterol-lowering agent. The first and second amounts comprise a therapeutically effective amount. The pharmaceutical compositions of the present invention may optionally contain a pharmaceutically acceptable carrier. |
申请公布号 |
AU3988099(A) |
申请公布日期 |
2000.12.05 |
申请号 |
AU19990039880 |
申请日期 |
1999.05.13 |
申请人 |
GELTEX PHARMACEUTICALS, INC. |
发明人 |
CHAD CORI HUVAL;STEPHEN RANDALL HOLMES-FARLEY;JOHN S PETERSEN;PRADEEP K. DHAL |
分类号 |
A61K31/785;A61K45/06;A61P9/10 |
主分类号 |
A61K31/785 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|