发明名称 |
PROCESS AND INTERMEDIATES FOR PREPARING ANTI-CANCER COMPOUNDS |
摘要 |
<p>The present invention relates to methods and intermediates for preparing compounds of the formula 1 <CHEM> and the pharmaceutically acceptable salts and solvates thereof, as well as structurally related compounds, wherein R<1>, R<2> and R<15> are as defined herein. The foregoing compounds are useful in the treatment of hyperproliferative disorders, such as cancers, in mammals. The present invention also relates to a method of preparing compounds of the formula 9 <CHEM> and the pharmaceutically acceptable salts and solvates thereof, wherein R<6>-R<10> and R<15> are as defined herein.</p> |
申请公布号 |
HU0001353(A3) |
申请公布日期 |
2002.01.28 |
申请号 |
HU20000001353 |
申请日期 |
2000.03.30 |
申请人 |
PFIZER PRODUCTS INC., GROTON, CONNECTICUT |
发明人 |
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分类号 |
C07D239/94;A01N43/54;A61K;A61K31/00;A61K31/33;A61K31/40;A61K31/498;A61K31/505;A61K31/517;A61P35/00;C07B61/00;C07D;C07D235/14;C07D239/70;C07D239/72;C07D239/74;C07D239/95;C07D401/00;C07D403/00;C07D405/00;C07D409/00;C07D413/00;C07D417/00;C07D419/04;C07D455/02;C07D471/04;C07D473/00;C07D475/00;C07D491/048;C07F7/08;C07F7/10;C22B3/04;C22B15/00 |
主分类号 |
C07D239/94 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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