| 发明名称 |
PROCESS FOR PREPARING 5-BIPHENYL-4-AMINO-2-METHYL PENTANOIC ACID |
| 摘要 |
<p>The present invention relates to pyrrolidin-2-ones according to the formu la (1), or salts thereof, wherein R1 is hydrogen or a nitrogen protecting gr oup, methods for their preparation and their use in the preparation of NEP-i nhibitors, particularly in the preparation of N-(3-carboxyl-1-oxopropyl)-(4S )-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester or sa lt thereof.</p> |
| 申请公布号 |
CA2674291(A1) |
申请公布日期 |
2008.07.17 |
| 申请号 |
CA20082674291 |
申请日期 |
2008.01.10 |
| 申请人 |
NOVARTIS AG |
发明人 |
RUCH, THOMAS;HOOK, DAVID;CISZEWSKI, LECH;SEDELMEIER, GOTTFRIED;WAYKOLE, LILADHAR MURLIDHAR;HAWKER, STEVEN;BANZIGER, MARKUS;NAPP, MATTHIAS;RISS, BERNHARD;WIETFELD, BERNHARD |
| 分类号 |
C07C227/22;C07C227/16;C07C227/32;C07C229/34;C07C269/06;C07C271/22;C07D207/26;C07D207/267;C07D207/27;C07D207/277;C07D207/28;C07D207/38;C07D207/44;C07D227/02;C07F7/18 |
主分类号 |
C07C227/22 |
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