| 摘要 |
PROBLEM TO BE SOLVED: To obtain a crosslinked aliphatic polyoxamide comprising the crosslinked product of a specific aliphatic polyoxamide, capable of exhibiting excellent bioabsorbability, steam penetrability and biodegradability and useful for surgery devices such as suture, shaping devices, lubricants, etc. SOLUTION: This crosslinked aliphatic polyoxamide comprises the crosslinked product of an aliphatic polyoxamide having (U1 ) a repeating unit of formula I [X is O, a group of the formula: N(R) (R is H, a 1-8C alkyl); R1 , R2 are each R; R3 is an alkylene unit, etc.,] and (U2 ) a repeating unit of formula II (Y is X, wherein Y and X are simultaneously not O; R17 is a 2-8C alkylene which may have an ethereal O in the chain, etc.; T is 1-2000), a repeating unit of formula III [R5 is (CH2 )3 -O, CH2 -CH2 -O-CH2 , etc.; B is such a number as giving a number-average mol.wt. (Mn) of <200,000], a repeating unit of formula IV (R9 is R5 ; G is a residue obtained by removing 1-200 hydrogen atoms from the hydroxyl groups of an alcohol having 1-200 hydroxyl groups; P is such a number as giving an Mn <1,000,000; L is 1-200) or their combination. |
