| 摘要 |
Disclosed is a solid dispersion of the selective ErbB2 (HER2) inhibitor N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine (ARRY -380) and processes for preparing the solid dispersion. Also disclosed are pharmaceutical compositions comprising a solid dispersion of N4-(4-([1,2,4]triazolo[1,5-α]pyridin-7-yloxy)-3- methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine for treating cancer. |
