主权项 |
1. A method for preparing a high-strength biological scaffold material, characterized in that, the method comprises the following steps:
boiled-off silk obtained by degumming silk is woven into a woven material by a textile machine to form a framework according to the desired shape, and then the framework is placed into a mold; a solution containing silk fibroin is injected into the mold having the framework placed therein, and subjected to freezing and vacuum treatment; thereby a coating layer having a thickness of 100 microns to 5 cm is formed on the surface of the framework, and the high-strength biological scaffold material is prepared, wherein said solution containing silk fibroin is one selected from the group consisting of: an aqueous silk fibroin solution, a mixed solution of silk fibroin and gelatin, and a mixed solution of silk fibroin and collagen; the weave density of the woven material is such that the distance between adjacent boiled-off silks is between 0.5 mm and 3 mm, and the material of the coating layer is selected from the group consisting of: silk protein scaffold material, silk fibroin/gelatin biological scaffold material or silk fibroin/collagen biological scaffold material. |