| 摘要 |
PURPOSE: To obtain an organ preservation liquid having a specific solution osmolarity, containing a specific hydroxyethyl starch, capable of preserving a kidney, a pancreas and a liver and usable for simple cold-temperature preservation or a continuous perfusion. CONSTITUTION: This is a liquid for preserving or storing an organ to be used in implantation for a patient needing implantation. The liquid contains a lactobionate and raffinose as an impermeability agent against cells, has a solution osmolarity of about 320mOsm/L and contains K<+> of 120mM and Na<+> of 30mM. Further, the liquid is substantially free from ethylene glycol, ethylene chlorohydrin, sodium chloride and acetone, and contains a hydroxyethyl starch having an average molecular weight of 150,000-350,000 dalton, preferably 200,000-300,000 dalton and a degree of substitution of 0.4-0.7 in an amount of about 5wt.%. It is preferable that the starch is free from a hydroxyethyl starch having a molecular weight of less than 50,000 dalton.
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