| 摘要 |
PURPOSE:To provide the preventive for gingivitis, by using an organic solvent- soluble fraction of a crude drug of Zingiberaceae family. CONSTITUTION:One or more kinds of crude drugs of Zingiberaceae faimly [e.g. SHOKYO (rhizome of Zingiber officinale), KANKYO (dried rhizome of Zingiber officinale), SHUKUSHA (fruit of Amomum xanthioides), YAKUCHI (fruit of Alpinia oxyphylla), SHOUZUKU (fruit of Elettaria cardamomum), KOUZUKU (fruit of Alpinia galanga), etc.] are extracted with an organic solvent, preferably a polar solvent (e.g. ethanol, acetone, ethyl acetate, etc.). The amount of the solvent is preferably >=3pts.wt. per 1pt. of the dried crude drug, and the extraction is carried out preferably at 25-45 deg.C for >=1hr, especially for 12-24hr. The extraction is repeated preferably twice or thrice to obtain the Zingiber crude drug fraction soluble in an organic solvent. The objective preventive for gingivitis can be prepared by using the fraction as a component. In the case of using the agent as a composition for oral cavity application, the amount of the agent is preferably 0.001-10wt% of the whole composition in terms of the extract. It can be used in the form of tooth paste, tooth powder, mouth wash, troche, tablet for gargling, etc. |
