TRINDENE COMPOUNDS

摘要

Described are trindene derivatives of formula (I), wherein X is methylene or carbonyl, R1 is hydrogen, acyl or unsubstituted or substituted alkyl, R'1 is hydrogen or lower alkyl, R2 is carboxy or functionally modified carboxy, R3 is hydrogen, halogen, amino, acyl, alkyl or aralkyl, R4 and R5 independent of each other are hydrogen, hydroxy, nitro, amino, lower alkyl, lower alkoxy, carbamoyl or halogen, and R6 is hydrogen or nitro, and salts thereof, a process for the preparation of these compounds, pharmaceutical compositions comprising these compounds and the preparation thereof, and the use of these compounds and compositions for the therapeutic treatment of the human or animal body.