| 摘要 |
<p>NEW MATERIAL:A compound expressed by formula I (Lys is L-lysine; R<1> is benzyloxycarbonyl or H; R<2> is cyclohexyl or benzyl). EXAMPLE:A H-Lys-Lys-NHBzl acetic acid salt expressed by the formula. USE:An antiallergic agent. PREPARATION:The aimed compound is obtained by subjecting a lysine derivative expressed by formula II to condensation reaction with a lysine derivative expressed by formula III (X<2> is amino protecting group) preferably in the presence of equimolar amounts of dicyclohexylcarbodiimide and N-hydrosuccinic imide normally in a solvent such as chloroform, DMF at -30-50 deg.C.</p> |
