22ORGANOTHIOO22CYCLOPENTENONES* ORGANOOTHIOCYCLOPENTANES DERIVED FROM THEM AND THEIR PREPARATION

摘要

PURPOSE:2-Organothio-2-cyclopentenones of formula I (R is monovalent organic radical of C1-25, Z is H, OH, protected OH), e.g. 4-t-butyl-dimethylsiloxy2-n-octylthiocyclopent-2-en-1-one, and organothiocyclopentanes of formula II [E is C=O, C(Z')H (Z' is H, OH, etc.); X is S, CH2, CH, the dotted line indicates a single or double bond, R' is mono- or divalent organic radical], e.g. 11-deoxy7-thiaprostaglandin E1 methyl ester.