发明名称 |
NOVEL THERAPEUTIC AGENT FOR SEPTICEMIA, AND A METHOD FOR SCREENING FOR SAME |
摘要 |
Provided are: a therapeutic agent for septicemia and/or septic shock; and a method for screening for same. The present invention pertains to a therapeutic agent for septicemia and/or septic shock, containing, as an active ingredient, an Arid5A inhibitor. The present invention is also a method for screening for candidate substances effective in the treatment of septicemia and/or septic shock, said method comprising: (a) a step of evaluating the impact of a test substance on the expression and/or function of Arid5A; and (b) a step which involves the selection of a substance that reduces the expression and/or function of Arid compared to a case in which the test substance is not used. |
申请公布号 |
WO2016104490(A1) |
申请公布日期 |
2016.06.30 |
申请号 |
WO2015JP85806 |
申请日期 |
2015.12.22 |
申请人 |
KISHIMOTO, TADAMITSU;MASUDA, KAZUYA;CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
KISHIMOTO, TADAMITSU;MASUDA, KAZUYA |
分类号 |
A61K45/00;A61K31/7088;A61K31/713;A61K39/395;A61K48/00;A61P31/00;A61P43/00;C07K16/18;C12N15/09;C12N15/113;C12N15/115;C12Q1/68;G01N33/15;G01N33/50 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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