发明名称 NOVEL THERAPEUTIC AGENT FOR SEPTICEMIA, AND A METHOD FOR SCREENING FOR SAME
摘要 Provided are: a therapeutic agent for septicemia and/or septic shock; and a method for screening for same. The present invention pertains to a therapeutic agent for septicemia and/or septic shock, containing, as an active ingredient, an Arid5A inhibitor. The present invention is also a method for screening for candidate substances effective in the treatment of septicemia and/or septic shock, said method comprising: (a) a step of evaluating the impact of a test substance on the expression and/or function of Arid5A; and (b) a step which involves the selection of a substance that reduces the expression and/or function of Arid compared to a case in which the test substance is not used.
申请公布号 WO2016104490(A1) 申请公布日期 2016.06.30
申请号 WO2015JP85806 申请日期 2015.12.22
申请人 KISHIMOTO, TADAMITSU;MASUDA, KAZUYA;CHUGAI SEIYAKU KABUSHIKI KAISHA 发明人 KISHIMOTO, TADAMITSU;MASUDA, KAZUYA
分类号 A61K45/00;A61K31/7088;A61K31/713;A61K39/395;A61K48/00;A61P31/00;A61P43/00;C07K16/18;C12N15/09;C12N15/113;C12N15/115;C12Q1/68;G01N33/15;G01N33/50 主分类号 A61K45/00
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