Method and device for the measurement and the elimination of system changes in a device for the treatment of blood

摘要

The present invention relates to a method and a device for the measurement of pressure signals in a blood treatment system, whereby system changes can be identified and can be differentiated additionally reliably between system changes in blood flow direction and in transmembrane direction in order to enable a targeted action.

主权项

1. Method for the differentiation of disturbances of the flow resistance in a blood treatment system which comprises the following steps:
a) measuring at least two pressure signals selected from the group consisting of (PB1, PB2, PD1, PD2), which are measured at least two pressure sensors, which are selected from the group consisting of [PB1], [PB2], [PD1] and [PD2], wherein [PB1] represents the pressure sensor in the blood circulation before the blood inlet into the tangential flow filter TFF and PB1 represents the pressure measured at the pressure sensor [PB1], [PB2] represents the pressure sensor in the blood circulation after the blood outlet from the tangential flow filter TFF and PB2 represents the pressure measured at the pressure sensor [PB2], [PD1] represents the pressure sensor in the dialysate circulation before the dialysate inlet into the tangential flow filter TFF and PD1 represents the pressure measured at the pressure sensor [PD1] and [PD2] represents the pressure sensor in the dialysate circulation after the dialysate outlet from the tangential flow filter TFF and PD2 represents the pressure measured at the pressure sensor [PD2]; b) calculating the quotients and/or the differences from the pressure signals measured according to step a), wherein the quotients and/or the differences are calculated from the pressure signals selected from the group consisting of (PB1, PB2) and/or (PB1, PD1) and/or (PB1, PD2) and/or (PB2, PD1) and/or (PB2, PD2) and/or (PD1, PD2) and/or (PB1, PDM) and/or (PB2, PDM) and/or (PD1, PBM) and/or (PD2, PBM) and/or (PDM, PBM) in a central processing unit, wherein with PBM or PDM the respective average from (PB1,PB2) or (PD1, PD2) is represented; c) repeating, at least once, the steps a) and b), wherein at the same at least two pressure sensors as measured in the previous measurement and from the measured pressure signals the same quotients and/or differences are calculated; d) generating at least one time trend from the measured pressure signals selected from the group consisting of (PB1, PB2, PD1, PD2) and/or the calculated differences, and/or quotients of the pressure signals (PB1, PB2) and/or (PB1, PD1) and/or (PB1, PD2) and/or (PB2, PD1) and/or (PB2, PD2) and/or (PD1, PD2) and/or (PB1, PDM) and/or (PB2, PDM) and/or (PD1, PBM) and/or (PD2, PBM) and/or (PDM, PBM); e) evaluating the at least one time trend, whether a change of the at least one time trend has occurred over a tolerance range; f) generating a pattern for the evaluation of the at least one time trend; g) assigning the pattern to a disturbance condition, such that a location and type of the disturbance condition within the blood treatment system is determined; h) displaying the disturbance condition on a display device of the central processing unit; and i) automatically eliminating, with the blood treatment system, the disturbance condition to return the flow resistance to within the tolerance range, if the system determines that the disturbance condition is of the type and location that can be automatically eliminated.