发明名称 |
NOVEL COMPOUNDS |
摘要 |
Putative Adrenomedulin Receptor polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclo sed are methods for utilizing Putative Adrenomedulin Receptor polypeptides and polynucle otides in the design of protocols for the treatment of infections such as bacterial, fungal, p rotozoan and viral infections, particularly infections caused by HIV-1 or HIV-2; pain; cancers; dia betes, obesity; anorexia; bulimia; asthma; Parkinson's disease; acute heart failure; hypotension ; hypertension; urinary retention; osteoporosis; angina pectoris; myocardial infarction; ulcers; asthma; allergies; benign prostatic hypertrophy; psychotic and neurological disorders, including an xiety, schizophrenia, manic depression, delirium, dementia, severe mental retardation a nd dyskinesias, such as Huntington's disease or Gilles dela Tourett's syndrome; and pre-eclampsi a, among others and diagnostic assays for such conditions.
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申请公布号 |
CA2242308(A1) |
申请公布日期 |
1999.06.08 |
申请号 |
CA19982242308 |
申请日期 |
1998.08.28 |
申请人 |
SMITHKLINE BEECHAM CORPORATION;SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES |
发明人 |
POSTE, GEORGE HENRY;ROBERT, PHILIPPE LAURENT;SOUCHET, MICHEL LOUIS;MAHE, EVE;GOUT, BERNARD EMILE JOSEPH;KRIEF, STEPHANE CLEMENT |
分类号 |
G01N33/50;A61K31/00;A61K31/70;A61K38/00;A61K38/22;A61K39/395;A61K45/00;A61K48/00;A61P1/00;A61P1/04;A61P3/00;A61P3/04;A61P3/10;A61P9/00;A61P9/02;A61P9/10;A61P9/12;A61P11/00;A61P11/06;A61P13/00;A61P13/02;A61P13/08;A61P19/00;A61P19/10;A61P25/04;A61P25/08;A61P25/14;A61P25/16;A61P25/22;A61P25/24;A61P25/28;A61P31/00;A61P31/04;A61P31/10;A61P31/12;A61P35/00;A61P37/00;A61P37/08;A61P43/00;C07K14/705;C07K14/72;C07K16/28;C12N5/10;C12N15/09;C12N15/16;C12P21/02;C12Q1/68;C12R1/91;G01N33/15;G01N33/566;(IPC1-7):C12N15/16 |
主分类号 |
G01N33/50 |
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