This invention is based, at least in part, on the discovery of a novel nuclear protein which contains both PDZ and LIM domains, SLIM (STAT-interacting LIMP. SLIM interacts with activated STAT molecules. The invention also provides methods of using these novel SLIM compositions. The invention also provides therapeutic methods involving the SLIM nucleic acid and protein molecules of the invention.
申请公布号
WO2006094293(A2)
申请公布日期
2006.09.08
申请号
WO2006US08121
申请日期
2006.03.03
申请人
PRESIDENT AND FELLOWS OF HARVARD COLLEGE;GRUSBY, MICHAEL, J.;TANAKA, TAKASHI