ghis invention relates to a novel advantageous process for the stereoselective preparation of 2-hydroxy-4-phenylbutyrates (HPB esters) and of their precursors. This is done by starting from readily accessible alpha -unsaturated alpha -hydroxy- gamma -keto esters which can be prepared by Claisen condensation.
申请公布号
WO9950223(A3)
申请公布日期
1999.11.18
申请号
WO1999EP01915
申请日期
1999.03.22
申请人
CIBA SPECIALTY CHEMICALS HOLDING, INC.;STUDER, MARTIN;HEROLD, PETER;INDOLESE, ADRIANO;BURCKHARDT, STEFAN
发明人
STUDER, MARTIN;HEROLD, PETER;INDOLESE, ADRIANO;BURCKHARDT, STEFAN