| 摘要 |
A low prime membrane oxygenator (150) and an integrated heat exchanger/reservoir (24, 40) for use alone or in combination in an extracorporeal blood circuit. The oxygenator has a simple, five-part construction including a housing (152) defining an annular oxygenation chamber (168) within which a plurality of hollow fibers (160) are arranged in an annular bundle with flow spaces therebetween. A blood inlet port and manifold deliver blood through a plurality of evenly circumferentially spaced inlet apertures to the oxygenation chamber, and blood flows generally axially through the elongated annular chamber to a plurality of evenly circumferentially spaced outlet apertures. Specific geometric ratios, a particular hollow fiber architecture, and the absence of a heat exchange function, all combine to reduce the prime volume required by the oxygenator. The reservoir (24, 40) includes heat exchange coils (88) in an annular chamber (86) providing efficient heat transfer with low prime volume. |
