| 摘要 |
The present invention relates to the field of nuclear medicine and in particular to the application of the monoclonal antibody ior C5 for the diagnosis and therapy of colorectal tumors, their metastases and recurrences. To this effect, the present invention provides a composition which contains monoclonal antibodies which recognize the antigen ior C2 and a weak ligand with the reducer agent Sn<2+> in order to transfer Tc-99m, Re-186, Re-188 and analogs thereof, said composition being useful for the diagnosis by immunogammagraphy and radioimmunotherapy of colorectal tumors, metastases and recurrences.
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| 申请人 |
CENTRO DE INMUNOLOGIA MOLECULAR (CIM);IZNAGA ESCOBAR, NORMANDO ENRIQUE;MORALES MORALES, ALEJO ANTONIO,;NUNEZ GANDOLFF, GILDA,;RAMOS ZUZARTE, MAYRA,;VAZQUEZ LOPEZ, ANA MARIA,;TORMO BRAVO, BLANCA ROSA;OLIVA GONZALEZ, JUAN PERFECTO,;RODRIGUEZ MESA, NELSON VICTOR,;LOMBARDERO VALLADARES, JOSEFA,;MATEO DE ACOSTA DEL RIO, CRISTINA |
发明人 |
IZNAGA ESCOBAR, NORMANDO ENRIQUE;MORALES MORALES, ALEJO ANTONIO,;NUNEZ GANDOLFF, GILDA,;RAMOS ZUZARTE, MAYRA,;VAZQUEZ LOPEZ, ANA MARIA,;TORMO BRAVO, BLANCA ROSA;OLIVA GONZALEZ, JUAN PERFECTO,;RODRIGUEZ MESA, NELSON VICTOR,;LOMBARDERO VALLADARES, JOSEFA,;MATEO DE ACOSTA DEL RIO, CRISTINA |
