| 发明名称 |
Development of mutations useful for attenuating dengue virses and chimeric dengue viruses |
| 摘要 |
A menu of mutations was developed that is useful in fine-tuning the attenuation and growth characteristics of dengue virus vaccines. |
| 申请公布号 |
AU2002312011(B2) |
申请公布日期 |
2008.04.24 |
| 申请号 |
AU20020312011 |
申请日期 |
2002.05.22 |
| 申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
KATHRYN A. HANLEY;STEPHEN S. WHITEHEAD;BRIAN R. MURPHY;JOSEPH E JR BLANEY |
| 分类号 |
A61K39/12;A61K39/193;A61K39/295;C07H21/04;C07K1/00;C07K14/00;C07K17/00;C12N7/00;C12N7/01;C12N7/04;C12Q1/68;C12Q1/70 |
主分类号 |
A61K39/12 |
| 代理机构 |
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