Combined interferon alfa and lipsosmal-encapsulated all-trans retinoic acid, including preparation and use

摘要

Alfa interferon (alpha-IFN or alpha-interferon) and liposomal all-trans retinoic acid is useful in cancer treatment with particular reference to renal cancer. Optionally, a regimen of alpha-interferon from about 3 to about 5 million units sc daily and liposomal all-trans retinoic acid at from about 15 mg/m2 to about 90 mg/m2, or about 140 mg/m2, or about 300 mg/m2 or more. Dosage periodicity of about three times per week for both drugs in about 8 week cycles is useful.