发明名称 |
Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia |
摘要 |
A method of using an MMP inhibitor and optionally radiation therapy, and one or more antineoplastic agents of the topoisomerase class selected from the group consisting of irinotecan and topotecan, as a combination therapy for the treatment of neoplasia is disclosed.
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申请公布号 |
US6858598(B1) |
申请公布日期 |
2005.02.22 |
申请号 |
US20010857995 |
申请日期 |
2001.10.05 |
申请人 |
G. D. SEARLE & CO. |
发明人 |
MCKEARN JOHN P.;GORDON GARY;CUNNINGHAM JAMES J.;GATELY STEPHEN T.;KOKI ALANE T.;MASFERRER JAIME L. |
分类号 |
A61K31/135;A61K31/415;A61K31/42;A61K31/445;A61K31/505;A61K31/506;A61K31/675;A61K33/24;A61K41/00;A61K45/06;(IPC1-7):A61K31/33;C07D295/00;C07D211/00;C07D417/00 |
主分类号 |
A61K31/135 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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