发明名称 |
PHARMACEUTICAL PARENTERAL COMPOSITION CONTAINING A BIPHOSPHONATE |
摘要 |
The present invention relates to a parenteral composition comprising a bisphosphonic acid or a pharmaceutically acceptable salt thereof (bisphosphonate) as active component and a pharmaceutically acceptable chelating agent, processes of the preparation of this composition, and methods of their use in the treatment a nd prevention of diseases involving bone resorption, especially osteoporosis, Paget's disease, hypercalcemia of malignancy, and metabolic bone disease. The compositions are especially useful for improving the local tolerance of the active component when administered parenterally.
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申请公布号 |
CA2406798(C) |
申请公布日期 |
2008.04.29 |
申请号 |
CA20012406798 |
申请日期 |
2001.01.16 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
PFISTER, THOMAS;DIEDERICH, ANKE;GOLDBACH, PIERRE |
分类号 |
A61K31/663;A61K47/04;A61K9/08;A61K31/167;A61K31/66;A61K31/675;A61K45/00;A61K47/10;A61K47/12;A61K47/18;A61K47/20;A61K47/22;A61K47/24;A61K47/26;A61P3/14;A61P19/08;A61P19/10;A61P23/02 |
主分类号 |
A61K31/663 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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