| 摘要 |
organic synthesis. SUBSTANCE: invention provides novel difluoromethylene compounds of general formula I: (I), in which R1 is hydrogen atom or C1-C10-alkyl; R5 methyl or ethyl; R2 hydrogen atom or C1-C10-alkyl in alpha- or beta- position; R3 hydrogen or C1-C10-alkoxy in alpha- or beta-position; R4 hydrogen in alpha- or beta-position; A,B,D,E, and G each are hydrogen atom and, if necessary, at least one of substituent pairs G and R2, R2 and R4, R4 and A, A and R3, D and E form double bond. Compound I exhibit antioxidant and vessel-protection properties and can be used for treatment and prophylaxis of a variety of afflictions. EFFECT: expanded assortment of useful biologically-active compounds. 12 cl, 2 dwg, 12 ex
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