发明名称 |
Single gene encoding aortic-specific and striated-specific muscle cell isoforms and uses thereof |
摘要 |
Aortic-preferentially-expressed gene-1 (APEG-1) and striated muscle preferentially expressed (SPEG) polypeptide, DNA sequences encoding and controlling the transcription of the APEG-1/SPEG encoding gene, methods of diagnosing vascular injury, methods of conferring smooth muscle-cell specific expression, and methods of inhibiting vascular smooth muscle cell proliferation by increasing the level of APEG-1 at the site of vascular injury.
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申请公布号 |
US5846773(A) |
申请公布日期 |
1998.12.08 |
申请号 |
US19970795868 |
申请日期 |
1997.02.06 |
申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
LEE, MU-EN;HSIEH, CHUNG-MING |
分类号 |
C12N15/09;A61K38/00;A61K48/00;C07K14/47;C12N5/10;C12N15/12;(IPC1-7):C12P21/02;C12N15/85;C12N15/11;C07H21/04 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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