| 发明名称 |
Quinoline compounds as H+-ATPases |
| 摘要 |
PCT No. PCT/JP96/02981 Sec. 371 Date Apr. 14, 1998 Sec. 102(e) Date Apr. 14, 1998 PCT Filed Oct. 15, 1996 PCT Pub. No. WO97/14681 PCT Pub. Date Apr. 24, 1996This invention relates to a quinoline compound of the formula: wherein R1 is a pyridyl group or aryl, each of which may be substituted with suitable substituent(s), A is -COHN- or -NHCO-, n is an integer of 0 or 1, and is a group of the formula: In which R2, R3, R4, R5, R6 and R7 are as defined, and pharmaceutically acceptable salt thereof, to processes for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for the prevention and/or the treatment of bone diseases caused by abnormal bone metabolism in human being or animals.
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| 申请公布号 |
US6008230(A) |
申请公布日期 |
1999.12.28 |
| 申请号 |
US19980051093 |
申请日期 |
1998.04.14 |
| 申请人 |
FUJISAWA PHARMACEUTICAL CO., LTD. |
发明人 |
OKU, TERUO;KAWAI, YOSHIO;SATOH, SHIGEKI;YAMAZAKI, HITOSHI;KAYAKIRI, NATSUKO;URANO, YASUHARU;YOSHIHARA, KOUSEI;YOSHIDA, NORIKO |
| 分类号 |
A61K31/00;A61K31/435;A61K31/4353;A61K31/4365;A61K31/47;A61K31/4706;A61K31/472;A61K31/4725;A61K31/4738;A61K31/4745;A61K31/495;A61K31/496;A61K31/505;A61K31/513;A61K31/517;A61K31/529;A61K31/535;A61K31/5375;A61K31/5377;A61K31/54;A61K31/542;A61P19/00;A61P19/08;C07D215/20;C07D215/40;C07D215/42;C07D215/44;C07D215/46;C07D215/48;C07D215/54;C07D215/56;C07D215/60;C07D221/12;C07D237/28;C07D239/74;C07D239/88;C07D239/94;C07D241/42;C07D401/04;C07D401/06;C07D401/12;C07D401/14;C07D403/04;C07D405/12;C07D409/12;C07D413/12;C07D417/12;C07D471/04;C07D495/04;C07D513/04;C07D513/14;C07D521/00;C07F7/08;C07F7/10;C07F7/18;(IPC1-7):C07D215/40 |
主分类号 |
A61K31/00 |
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