| 发明名称 | Method for preparing biological tissue | ||
| 摘要 | A method for preparing tissue for medical applications, in particular tissue for use for an artificial heart valve, wherein the method has the steps of decellularizing the tissue by means of a detergent and subsequently cross-linking the collagen fibers of the tissue by means of a suitable cross-linking agent. At least one lipopeptide, such as surfactin, for example, is used as the detergent for decellularization. | ||
| 申请公布号 | US9402934(B2) | 申请公布日期 | 2016.08.02 |
| 申请号 | US201414341783 | 申请日期 | 2014.07.26 |
| 申请人 | BIOTRONIK AG | 发明人 | Rzany Alexander;Erdbruegger Wilhelm |
| 分类号 | A61L27/36;A61L27/24 | 主分类号 | A61L27/36 |
| 代理机构 | Wagenknecht IP Law Group PC | 代理人 | Wagenknecht IP Law Group PC |
| 主权项 | 1. A method for preparing tissue for medical applications, comprising: decellularizing the tissue by means of a detergent, characterized in that the decellularizing detergent contains at least one amphiphilic lipopeptide comprising a hydrophilic base structure and a hydrophobic side chain; and subsequently cross-linking the collagen fibers of the tissue by means of a suitable cross-linking agent. | ||
| 地址 | Beulach CH | ||