发明名称 |
Control of aberrant expression vector accumulation during fermentation procedures. |
摘要 |
<p>The present invention provides a method for preventing the accumulation of aberrant expression vectors during fermentation processes which rely on the expression of an expression vector coded gene for production of a polypeptide product of interest. Antibiotics are added at approximately the time at which product expression begins.</p> |
申请公布号 |
EP0405858(A2) |
申请公布日期 |
1991.01.02 |
申请号 |
EP19900306853 |
申请日期 |
1990.06.22 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
MUTH, WILLIAM LAWRENCE |
分类号 |
C12P21/00;C07K14/61;C12N15/18;C12N15/67;C12N15/70;C12R1/19 |
主分类号 |
C12P21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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