METHOD FOR PURIFYING FACTOR VIII/VWF COMPLEX BY CATION-EXCHANGE CHROMATOGRAPHY

摘要

The invention relates to a method for obtaining factor VIII/vWF complex, characterized in that factor VIII/vWF complex from a protein solution is bonded with a cation-exchanger and factor VIII/vWF complex especially containing vWF multimers of high molecular weight is obtained by gradual elution. The invention also relates to a factor VIII/vWF complex which can be obtained by cation-exchange chromatography.