发明名称 |
BARBITURIC ACID DERIVATIVE AND PREVENTIVE AND THERAPEUTIC AGENT FOR BONE AND CARTILAGE CONTAINING THE SAME |
摘要 |
The present invention relates to a barbituric acid derivative shown in formula (I) (wherein R or R<1> independently represents a hydrogen atom, a susbstituted or not substituted alkyl group or alkenyl group of C1 - C15, a substituted or not substituted arylmethyl group, and substituted or not substituted aryl group, and R<2> represents substituted or not substituted alkyl group or alkenyl group of C1 - C15, a substituted or not substituted arylmethyl group, and substituted or not substituted aryl group). The barbituric acid derivative of the present invention has a strong inhibiting activity to bone resorption and is useful as a preventive and therapeutic agent for diseases affecting bone and cartilage. |
申请公布号 |
WO9950252(A2) |
申请公布日期 |
1999.10.07 |
申请号 |
WO1999IB00961 |
申请日期 |
1999.03.23 |
申请人 |
HOECHST MARION ROUSSEL;SAKAI, KUNIKAZU;SATOH, YUSUKE |
发明人 |
SAKAI, KUNIKAZU;SATOH, YUSUKE |
分类号 |
A61K31/505;A61P19/10;A61P29/00;A61P43/00;C07D239/62;C07D409/06 |
主分类号 |
A61K31/505 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|