发明名称 ADENOVIRUS FORMULATIONS FOR GENE THERAPY
摘要 <p>The present invention relates to a formulation allowing the preservation of viral particles and viral vectors, which is directly injectable into an organism. It relates more particularly to a formulation for the preservation of a recombinant adenovirus vector that optimally enhances the vector titer, or stabilizes the vector at refrigerator or room temperature, or both. The invention relates to compositions comprising a recombinant adenovirus vector and a concentration of human serum albumin (HSA) effective to stabilize the adenovirus vector at a temperature above the freezing point of water or to enhance a titer of the adenovirus vector compared to a titer in the absence of HSA, or both, in an aqueous buffer.</p>
申请公布号 WO2000009675(A1) 申请公布日期 2000.02.24
申请号 US1999018515 申请日期 1999.08.13
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