DNA VACCINE AGAINST H5N1 INFLUENZA VIRUS, MODIFIED NUCLEOTIDE SEQUENCE AND USE OF THE MODIFIED NUCLEOTIDE SEQUENCE IN VACCINE MANUFACTURING

摘要

The presented invention is related to a DNA vaccine against the H5N1 influenza virus, a modified nucleotide sequence and use of the modified nucleotide sequence in vaccine manufacturing. In more detail, the presented invention is related to use of a modification of an antigen coding sequence in order to increase efficiency of a DNA vaccine.