| 摘要 |
The present invention pertains to a spray dried spheroidal microcapsule under about 150 microns in diameter which comprises (a) a medicament present in an amount from about 1% to about 90%, by veight of the microcapsule composition, (b) a film forming polymer present in an amount from about 8% to about 90%, by weight of the microcapsule composition, and (c) a plasticizing agent present in an amount from about 5% to about 30%, by weight of the film forming polymer. In another embodiment, the invention is directed at a spheroidal coated microcapsule under about 850 microns in diameter which comprises at least one spray dried spheroidal microcapsule core under about 150 microns in diameter and a coating layer over the core, wherein the coating layer comprises (a) a film forming polymer, and (b) a plasticizing agent present in an amount from about 5% to about 30%, by weight of the film forming polymer. |
