发明名称 |
Humanized antibodies that recognize difucosyl Lewis blood group antigens Y-6 and B-7-2 |
摘要 |
Humanized monoclonal antibodies that recognize the difucosyl Lewis blood group antigens Y-6 and B-7-2 are disclosed. The antibodies have a humanized light chain variable region and a humanized heavy chain variable region with CDRs from antibody BR55-2. Fragments of the antibodies and pharmaceutical compositions containing them are also disclosed.
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申请公布号 |
US5562903(A) |
申请公布日期 |
1996.10.08 |
申请号 |
US19930053171 |
申请日期 |
1993.04.22 |
申请人 |
SANDOZ LTD. |
发明人 |
CO, MAN S.;LOIBNER, HANS |
分类号 |
A61K39/395;A61K38/00;A61P31/12;A61P31/18;A61P35/00;C07K16/30;C07K16/34;C07K16/46;C12N15/09;C12P21/08;C12R1/91;G01N33/53;G01N33/577;(IPC1-7):A61K39/395;C07K16/28 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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