METHODS FOR EX VIVO ADMINISTRATION OF DRUGS TO GRAFTS USING POLYMERIC NANOPARTICLES
摘要
Methods for ex vivo administration of drugs to grafts using polymeric micro- and nanoparticles and applications for these methods are described herein. The particles contain encapsulated molecules which are released locally at the site of implantation and function to prevent graft rejection or aid in the proper adaptation of the graft to the host. The disclosed methods may be used to inhibit or reduce hyperplasia and stenosis of vascular grafts or to prevent graft rejection.
申请公布号
WO2008109347(A2)
申请公布日期
2008.09.12
申请号
WO2008US55313
申请日期
2008.02.28
申请人
YALE UNIVERSITY;FONG, PETER, M.;SALTZMAN, W., MARK;FAHMY, TAREK, M.
发明人
FONG, PETER, M.;SALTZMAN, W., MARK;FAHMY, TAREK, M.