| 摘要 |
A cosmetic composition is provided comprising a suitable carrier and at least one thiol protease; at least a first serine protease derived from Aspergillus melleus; and at least a second serine protease. The thiol protease may be selected from papain, ficin, bromelain and actinidin. The first serine protease is derived from Aspergillus melleus, and is preferably Aspergillus melleus proteinase. The second serine protease is selected from the group consisting of subtilisin, trypsin and chymotrypsin. The synergistic combination of these three proteolytic enzyme activities - the trienzyme activity - in the compositions of the invention facilitates improved cosmetic epidermal conditioning and resurfacing. Methods of using the compositions and methods of reconstituting the desired trienzyme activity in situ are also provided. |
