| 发明名称 |
Liquid stable bovine virus vaccines |
| 摘要 |
The present invention discloses liquid stable bovine vaccines that comprise a live attenuated virus, in sucrose, arginine, and methionine. The present invention also discloses the manufacture of such vaccines and methods of protecting an animal by administration of such vaccines. |
| 申请公布号 |
US9393298(B2) |
申请公布日期 |
2016.07.19 |
| 申请号 |
US201414202194 |
申请日期 |
2014.03.10 |
| 申请人 |
Intervet Inc. |
发明人 |
Buchanan Sandhya;O'Connell Kevin |
| 分类号 |
A61K39/215;A61K39/155;A61K39/12;A61K39/00 |
主分类号 |
A61K39/215 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A liquid stable vaccine that comprises a live attenuated bovine virus, 20-40% (w/v) sucrose, 0.15 to 0.75 M arginine, and 0.025 to 0.3 M methionine; wherein the liquid stable vaccine has a pH of 6.0 to 8.0; and wherein the live attenuated bovine virus is selected from the group consisting of infectious bovine rhinotracheitis virus (IBR), parainfluenza type 3 virus (PI3), bovine respiratory syncytial virus (BRSV), and any combination thereof. |
| 地址 |
Madison NJ US |
