发明名称 |
Use of compacted nucleic acid nanoparticles in non-viral treatments of ocular diseases |
摘要 |
The present invention is a method of using compacted nucleic acid (such as DNA) nanoparticles for non-viral gene transfer to various tissues of the human eye or eyes of other mammals. These nanoparticles comprise, in one embodiment, a neutrally-charged complex containing a single molecule of plasmid DNA compacted with polyethylene glycol (PEG)-substituted poly lysine peptides.
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申请公布号 |
US2009011040(A1) |
申请公布日期 |
2009.01.08 |
申请号 |
US20080150986 |
申请日期 |
2008.05.02 |
申请人 |
NAASH MUNA I;COOPER MARK J |
发明人 |
NAASH MUNA I.;COOPER MARK J. |
分类号 |
A61K9/14;A61K31/7052;A61K48/00;A61P27/02 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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地址 |
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