| 发明名称 | Macrocycles | ||
| 摘要 | The invention provides macrocycles useful in chelating metal ions, particularly radionuclides, to provide metal ion complexes. The invention also provides methods of using the compounds and complexes of the invention, such as in therapeutic and diagnostic applications. | ||
| 申请公布号 | US9439984(B2) | 申请公布日期 | 2016.09.13 |
| 申请号 | US201314403401 | 申请日期 | 2013.03.14 |
| 申请人 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 发明人 | Raymond Kenneth N.;Xu Jide;Pham Tiffany A. |
| 分类号 | A61K51/04;C07D259/00;C07B59/00;C07D401/14 | 主分类号 | A61K51/04 |
| 代理机构 | Morgan, Lewis & Bockius LLP | 代理人 | Morgan, Lewis & Bockius LLP ;Esker Todd |
| 主权项 | 1. A macrocycle having the structure: wherein Ap1 and Ap2 are independently selected from wherein Rs comprises a solubilizing group; and R11 is methyl or ethyl; and each n is an integer independently selected from 2 and 3. | ||
| 地址 | Oakland CA US | ||