| 摘要 |
PURPOSE:To readily regulate particle diameter, skin layer thickness, etc., and simply obtain a microsponge suitable as sustained release carriers, etc., by suspension polymerizing a polymerizable monomer in the presence of a crosslinking agent and hydrophobic volatile solvent in water and drying the resultant polymer. CONSTITUTION:A polymerizable monomer selected from styrene, (meth)acrylic acid esters, vinyl acetate, etc., is subjected to in-situ polymerization in water in the presence of a crosslinking agent, e.g. divinylbenzene, ethylene dimethacrylate, etc., and a hydrophobic volatile solvent, e.g. hydrocarbon, ketones having >=150 deg.C boiling point, etc., at 50-95 deg.C polymerization temperature and 50-500rpm stirring speed and the resultant polymer is dried to evaporate the hydrophobic volatile solvent and afford the aimed microsponge having 5-500mum particle diameter.
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