A novel human metabotropic glutamate receptor (mGluR) protein is identified, sequenced, and cloned. The receptor may be used to screen for compounds that modulate the activity of the mGluR. The recombinant mGluR as well as compounds that modulate mGluR activity may be used in the diagnosis and treatment of neurological disorders and diseases.
申请公布号
WO9748724(A3)
申请公布日期
1998.03.26
申请号
WO1997US09025
申请日期
1997.02.20
申请人
NPS PHARMACEUTICALS, INC.
发明人
STORMANN, THOMAS, M.;SIMIN, RACHEL, T.;HAMMERLAND, LANCE, G.;FULLER, FORREST, H.